Effect of percutaneous nucleoplasty with coblation on phospholipase A2 activity in the intervertebral disks of an animal model of intervertebral disk degeneration: a randomized controlled trial

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Effect of percutaneous nucleoplasty with coblation on phospholipase A2 activity in the intervertebral disks of an animal model of intervertebral disk degeneration: a randomized controlled trial

BACKGROUND This randomized controlled trial was carried out to (1) evaluate the effect of nucleoplasty with coblation on the PLA2 activity in the degenerative intervertebral disks of an animal model and (2) explore the possible therapeutic mechanism of coblation in addition to the current theory, which focuses on decreasing the intradiskal pressure in the treatment of intervertebral disk degene...

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Histologic characterization of coblation nucleoplasty performed on sheep intervertebral discs.

OBJECTIVE To characterize the histologic effects of coblation nucleoplasty on sheep intervertebral discs. DESIGN In vitro histologic study. METHODS Five sheep lumbar discs treated with nucleoplasty and two control discs were evaluated. Specimens were received frozen and thawed to room temperature. A segment consisting of the intervertebral disc and vertebral body above and below the disc wa...

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ژورنال

عنوان ژورنال: Journal of Orthopaedic Surgery and Research

سال: 2015

ISSN: 1749-799X

DOI: 10.1186/s13018-015-0175-y